Impairments in functioning, social abilities, memory and emotions in children and adults with corpus callosum anomalies. Rehabilitation protocols. Psychomotor therapy. Literature review

Abstract

The purpose of this thematic literature review is to review recent international studies on the most common difficulties in functioning in children and adults with agenesis or dysgenesis of the corpus callosum.

It was done with a focus on common themes in the studies, namely daily functioning, social abilities, emotions, memory, language, detailed thinking, creativity, problem solving and decision making, psychological functioning and interhemispheric interactions. Some of the studies focus on some common characteristics of children and adults with agenesis of the corpus callosum and attention deficit hyperactivity disorder, and autism and Asperger syndrome. 34 of the most recent studies of the disorders are reviewed with the main goal of introducing the idea of ​​the relevance of this type of research on a global scale, as well as the almost complete lack of knowledge about the overall functioning of this population in the Bulgarian context. The need for ongoing rehabilitation with sequential steps throughout life for people living with corpus callosum agenesis or dysgenesis is deduced, and an attempt is made to propose rehabilitation protocols in early and middle childhood, as well as in adolescence and adulthood. Knowledge is expanded on the application of psychomotor therapy as a comprehensive care and rehabilitation indicated for this target group of children and adults.

Ключови думи: disabilities, agenesis, corpus callosum, rehabilitation, protocols, psychomotor therapy

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Bibliography

  1. Badaruddin DH, Andrews GL, Bölte S, Schilmoeller KJ, Schilmoeller G, Paul LK, Brown WS. Social and behavioral problems of children with agenesis of the corpus callosum. Child Psychiatry Hum Dev. 2007;38:287–302.
  2. Miller JS, Brown WS, Mangum RW, Nolty AAT, Paul LK. Adaptive behavior in primary agenesis of the corpus callosum. Res Dev Disabil. 2024;154:104862. doi:10.1016/j.ridd.2024.104862. PMID:39454245.
  3. Mangum RW, Miller JS, Brown WS, Nolte A, Paul LK. Daily executive function in agenesis of the corpus callosum. J Int Neuropsychol Soc. 2021. doi:10.1017/S1355617721000096.
  4. Brown WS, Panos A, Paul LK. Impulsivity, vigilance, and attention in agenesis of the corpus callosum. Neuropsychology. 2020. doi:10.1037/neu0000685.
  5. Symington SH, Paul LK, Symington MF, Ono M, Brown WS. Social cognition in individuals with agenesis of the corpus callosum. Soc Neurosci. 2010;5:296–308. doi:10.1080/17470910903462419.
  6. Paul LK, Schieffer B, Brown WS. Social processing deficits in agenesis of the corpus callosum: Narratives from the Thematic Apperception Test. Arch Clin Neuropsychol. 2004;19:215–25.
  7. Young CM, Folsom RC, Paul LK, Su J, Mangum R, Brown WS. Social cognition in agenesis of the corpus callosum: Computational linguistic analysis of the Awareness of Consequences Scale. Neuropsychology. 2019. doi:10.1037/neu0000512.
  8. Brown WS, Burnett K, Vaillancourt A, Paul LK. Appreciation of social norms in agenesis of the corpus callosum. Arch Clin Neuropsychol. 2020. doi:10.1093/arclin/acab003.
  9. Anderson LB, Paul LK, Brown WS. Emotional intelligence in agenesis of the corpus callosum. Arch Clin Neuropsychol. 2017;32(3):267–79. doi:10.1093/arclin/acx001.
  10. Bridgman MW, Brown WS, Spezio ML, Leonard MK, Adolphs R, Paul LK. Facial emotion recognition in agenesis of the corpus callosum. J Neurodev Disord. 2014;6:32. doi:10.1186/1866-1955-6-32.
  11. Paul LK, Lautzenhiser A, Brown WS, Spezio M, Neumann D, Adolphs R. Emotional arousal in agenesis of the corpus callosum. Int J Psychophysiol. 2006;61:47–56.
  12. Paul LK, Pazienza S, Brown WS. Alexithymia and somatization in agenesis of the corpus callosum. Soc Cogn Affect Neurosci. 2021. doi:10.1093/scan/nsab056.
  13. Paul LK, Erickson RL, Hartman JA, Brown WS. Memory functioning in individuals with agenesis of the corpus callosum. Neuropsychologia. 2016;86:183–92. doi:10.1016/j.neuropsychologia.2016.04.013.
  14. Erickson RL, Paul LK, Brown WS. Verbal learning and memory in agenesis of the corpus callosum. Neuropsychologia. 2014;60:121–30. doi:10.1016/j.neuropsychologia.2014.06.003.
  15. Paul LK, Van Lancker D, Schieffer B, Brown WS. Communicative deficits in individuals with agenesis of the corpus callosum: Nonliteral language and affective prosody. Brain Lang. 2003;85:313–24.
  16. Brown WS, Symington M, VanLancker D, Dietrich R, Paul LK. Paralinguistic processing in children with callosal agenesis: Emergence of neurolinguistic deficits. Brain Lang. 2005;93:135–9.
  17. Rehmel JL, Brown WS, Paul LK. Proverb comprehension in individuals with agenesis of the corpus callosum. Brain Lang. 2016;160:21–9. doi:10.1016/j.bandl.2016.07.001.
  18. Brown WS, Paul LK, Symington M, Dietrich R. Comprehension of humor in primary agenesis of the corpus callosum. Neuropsychologia. 2005;43:906–16.
  19. Renteria-Vazquez T, Brown WS, Kang C, Graves M, Castelli F, Paul LK. Social inferences in agenesis of the corpus callosum and autism: Semantic analysis and topic modeling. J Autism Dev Disord. 2021. doi:10.1007/s10803-021-04957-2.
  20. Turk A, Brown WS, Symington M, Paul LK. Social narratives in agenesis of the corpus callosum: Linguistic analysis of the Thematic Apperception Test. Neuropsychologia. 2011;49:43–50.
  21. Brown WS, Hoard M, Birath B, Graves M, Nolty A, Paul LK. Imaginative elaboration in agenesis of the corpus callosum: Topic modeling and perplexity. J Int Neuropsychol Soc. 2024;16:1–8. doi:10.1017/S1355617724000183.
  22. Brown WS, Paul LK. The corpus callosum and creativity revisited. Front Hum Neurosci. 2024;18:1443970. doi:10.3389/fnhum.2024.1443970. PMID:39328385; PMCID:PMC11424518.
  23. Brown WS, Anderson L, Symington MF, Paul LK. Decision-making in agenesis of the corpus callosum: Expectancy-valence in the Iowa Gambling Task. Arch Clin Neuropsychol. 2012;27:123–34.
  24. Su JJ, Paul LK, Graves M, Turner JM, Brown WS. Verbal problem-solving in agenesis of the corpus callosum: Analysis using semantic similarity. Neuropsychology. 2023;37(5):615–20. doi:10.1037/neu0000894. PMID:36862453.
  25. Marco EJ, Harrell KM, Brown WS, Hill SS, Jeremy RJ, Kramer JH, Sherr EH, Paul LK. Processing speed delays contribute to executive function deficits in individuals with agenesis of the corpus callosum. J Int Neuropsychol Soc. 2012;18:383–92.
  26. Paradiso S, Brown WS, Porcerelli JH, Tranel D, Adolphs R, Paul LK. Integration between cerebral hemispheres contributes to defense mechanisms. Front Psychol. 2020;11:1534. doi:10.3389/fpsyg.2020.01534.
  27. Kaplan J, Kendrick SM, LeFebre NM, Brown WS, Hart A, Adolphs R, Paul LK. The corpus callosum and psychosocial functioning: MMPI-2-RF in callosal agenesis. In preparation.
  28. Mueller KO, Marion SD, Paul LK, Brown WS. Bimanual motor coordination in agenesis of the corpus callosum. Behav Neurosci. 2009;123:319–26. doi:10.1037/a0016868.
  29. Brown WS, Jeeves MA, Dietrich R, Burnison DS. Bilateral field advantage and evoked potential interhemispheric transmission in commissurotomy and callosal agenesis. Neuropsychologia. 1999;37:1154–80.
  30. Hines RJ, Paul LK, Brown WS. Spatial attention in agenesis of the corpus callosum: Shifting attention between visual fields. Neuropsychologia. 2002;40:1804–14.
  31. Brown WS, Bjerke MD, Galbraith GC. Interhemispheric transfer in normals and acallosals: Latency adjusted evoked potential averaging. Cortex. 1998;34:677–92.
  32. Дункова В. Продължаващо проучване за възможностите и ограниченията на рехабилитационната среда в България за подкрепа на деца със специални потребности. 2020.

Address for correspondence:

Ваня Дункова

София

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