Articles, Issue 2/2022

Chronic hepatitis B – Treatment of the Mother, Prevention of the Newborn

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R. Komitova, A. Kevorkyan, M. Atanasova, E. Golkocheva-Markova


Аbstract

The mother-to-child transmission of hepatitis B virus (HVB), frequent in endemic countries, accounts for about 40-50% of chronic HBV infections worldwide. Therefore, blocking the transmission is a significant step toward eliminating hepatitis B. The study presented a case of a successfully prophylactic baby girl born to a mother with chronic HBV infection diagnosed during pregnancy. She was prescribed antiviral therapy in the last trimester. The child was followed-up by the authors, proving her protection against HBV. In addition, we collected epidemiological data from family household contacts. The results  revealed  the source of the infection –  the grandmother of the baby with chronic HBV infection.

Кеy words:  hepatitis B virus, perinatal transmission, antiviral prophylaxis, hepatitis B vaccine, hepatitis B immunoglobulin

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Address for correspondence:

Department of Infectious diseases,
Parasitology and Tropical medicine, Faculty of Medicine,
Medical University
15A, Vassil Aprilov, Blvd.
4000, Plovdiv, Bulgaria
e-mail: radka.komitova@yahoo.com