{"id":1601,"date":"2023-12-19T15:20:00","date_gmt":"2023-12-19T13:20:00","guid":{"rendered":"https:\/\/pediatria-spisanie.eu\/2023\/12\/19\/digitalna-rentgenova-radiogrammetria\/"},"modified":"2025-05-18T23:24:26","modified_gmt":"2025-05-18T20:24:26","slug":"digitalna-rentgenova-radiogrammetria","status":"publish","type":"post","link":"https:\/\/pediatria-spisanie.eu\/en\/2023\/12\/19\/digitalna-rentgenova-radiogrammetria\/","title":{"rendered":"Digital X-ray Radiogrammetry (DXR) \u2013 a New and Accessible Method for Bone Health Screening in Pediatric Patients"},"content":{"rendered":"\n\n\t\t<div class=\"icon-box featured-box icon-box-left text-left is-small\"  >\n\t\t\t\t\t<div class=\"icon-box-img\" style=\"width: 20px\">\n\t\t\t\t<div class=\"icon\">\n\t\t\t\t\t<div class=\"icon-inner\" >\n\t\t\t\t\t\t<img decoding=\"async\" width=\"48\" height=\"48\" src=\"https:\/\/pediatria-spisanie.eu\/wp-content\/uploads\/2024\/12\/icons8-user-48.png\" class=\"attachment-medium size-medium\" alt=\"\" \/>\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t<div class=\"icon-box-text last-reset\">\n\t\t\t\t\t\t\t\t\t\n<h3> O. Slavcheva &#8211; Prodanova <\/h3>\n<p> <\/br>\n<\/p>\n\t\t<\/div>\n\t<\/div>\n\t\n\t\n<div class=\"is-divider divider clearfix\" ><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Abstract<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Childhood and adolescence are periods of active bone turnover and time for peak bone mass<br>acquisition. Peak bone mass is an important determining factor for bone health and future osteoporosis.<br>That\u2019s why optimizing peak bone mass accrual is of great importance. Many chronic conditions in childhood and adolescence, e.g. type 1 diabetes mellitus, cystic fibrosis, oncologic diseases etc. and\/or their treatment lead to impaired bone health Finding \u0430 sensitive, accessible, non-invasive and last but not least &#8211; inexpensive method for early screening of these disturbances is very important for the pediatric practice. Digital X-ray radiogrammetry is a comparatively new method, based on a well-known old one &#8211;<br>conventional radiogrammetry. Computer software provides information about bone density by determination of cortical thickness of three metcarpal bones. Data obtained by this method is very well correlated with the gold standard for bone density assessment, both in adults and children &#8211; dual energy X-ray absorptiometry.<br>Unlike it, the data from digital X-ray radiogrammetry do not need further adjustment for the pediatric patients. The result is compared to big data base of healthy children and can be used as indication for starting treatment and\/or further monitoring of that treatment. The method of digital X-ray radiogrammetry was used for the first time in Bulgaria in children and adolescents with type 1diabetes and shows promising results so far.<br><strong>Key words:<\/strong> bone health, screening, digital X-ray radio-grammetry<\/p>\n\n\n<div class=\"is-divider divider clearfix\" ><\/div>\n\n\n\t\t<div class=\"wp-block-woocommerce-memberships-member-content\">\n\t\t\t\t\t<div class=\"woocommerce\">\n\t\t\t<div class=\"woocommerce-info wc-memberships-restriction-message wc-memberships-message wc-memberships-content-restricted-message\">\n\t\t\t\tTo access this content, you must purchase <span class=\"wc-memberships-products-grant-access\"><a href=\"https:\/\/pediatria-spisanie.eu\/en\/produkt\/godishen-abonament\/\">\u0413\u043e\u0434\u0438\u0448\u0435\u043d \u0430\u0431\u043e\u043d\u0430\u043c\u0435\u043d\u0442<\/a><\/span>.\t\t    <\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\n\n\n<h2 class=\"wp-block-heading\"><strong>Bibliography<\/strong><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Heaney RP, Abrams S, Dawson-Hughes B et al. 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Pediatric Radiology. 2016;46(7):1017-22.<\/li>\n\n\n\n<li>Mentzel HJ, John U, Boettcher J et al. Evaluation of bone-mineral density by digital X-ray radiogrammetry (DXR) in pediatric renal transplant recipients. Pediatric radiology. 2005;35(5):489-94.<\/li>\n\n\n\n<li>Matkovic V, Goel PK, Badenhop-Stevens NE et al. Calcium supplementation and bone mineral density in females from childhood to young adulthood: a randomized controlled trial. The American journal of clinical nutrition. 2005 Jan 1;81(1):175-88.<\/li>\n\n\n\n<li>Hyldstrup L, Conway G, Racz K et al.Growth hormone effects on cortical bone dimensions in young adults with childhood-onset growth hormone deficiency.Osteoporosis International.2012.23:2219-2226.<\/li>\n\n\n\n<li>Craig ME, Jefferies C, Dabelea D et al.Definition, epidemiology, and classification of diabetes in children and adolescents. Pediatric Diabetes 2014: 15 (Suppl. 20): 4\u201317.<\/li>\n\n\n\n<li>Weber DR, Haynes K, Leonard MB et al. Type 1 diabetes is associated with an increased risk of fracture across the life span: a population-based cohort study using The Health Improvement Network (THIN). Diabetes care. 2015 Oct 1;38(10):1913-20.<\/li>\n\n\n\n<li>Kordonouri O, Klingensmith G, Knip M et al. Other complications and&nbsp; diabetes\u2010associated conditions in children and adolescents. Pediatric diabetes. 2014&nbsp; Sep;15(S20):270-8.<\/li>\n\n\n\n<li>Slavcheva\u2010Prodanova O, Konstantinova M, Tsakova A et al. Bone Health Index and bone turnover in pediatric patients with type 1 diabetes mellitus and poor metabolic control. Pediatric Diabetes. 2020 Feb;21(1):88-97.<\/li>\n<\/ol>\n\n\n<div class=\"is-divider divider clearfix\" ><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Address for correspondence:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Clinic for Pediatric Endocrinology and metabolic diseases<br>University Children\u2019s Hospital \u201cProf. I. Mitev\u201d, Sofia<br>11,\u201dAcad. I. Geshov\u201d, Blvd.<br>1431, Sofia, Bulgaria<br>e-mail: <a href=\"mailto:olga.slavcheva@yahoo.com\">olga.slavcheva@yahoo.com<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u00a0\u00a0\u00a0\u00a0\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>O. Slavcheva &#8211; Prodanova<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_pediatria_doi":"","footnotes":""},"categories":[1301,1341],"tags":[1787,1788,1789,1427,1790,1791,1792,1793,1437],"class_list":["post-1601","post","type-post","status-publish","format-standard","hentry","category-articles","category-issue-4-2023","tag-bone-health-en","tag-digital-x-ray-radiogrammetry-en","tag-dxr-nov-i-dostapen-metod-za-skrining-na-kostnoto-zdrave-v-detskata-vazrast-en","tag-screening-en","tag-digitalna-rentgenova-radiogrammetriya-en","tag-digitalnata-rentgenova-radiogrammetriya-digital-x-ray-radiogrammetry-en","tag-kostno-zdrave-en","tag-o-slavcheva-prodanova-en","tag-skrining-en"],"_links":{"self":[{"href":"https:\/\/pediatria-spisanie.eu\/en\/wp-json\/wp\/v2\/posts\/1601","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pediatria-spisanie.eu\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pediatria-spisanie.eu\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pediatria-spisanie.eu\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pediatria-spisanie.eu\/en\/wp-json\/wp\/v2\/comments?post=1601"}],"version-history":[{"count":1,"href":"https:\/\/pediatria-spisanie.eu\/en\/wp-json\/wp\/v2\/posts\/1601\/revisions"}],"predecessor-version":[{"id":1603,"href":"https:\/\/pediatria-spisanie.eu\/en\/wp-json\/wp\/v2\/posts\/1601\/revisions\/1603"}],"wp:attachment":[{"href":"https:\/\/pediatria-spisanie.eu\/en\/wp-json\/wp\/v2\/media?parent=1601"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pediatria-spisanie.eu\/en\/wp-json\/wp\/v2\/categories?post=1601"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pediatria-spisanie.eu\/en\/wp-json\/wp\/v2\/tags?post=1601"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}