Брой 2/2022, Статии

Off-label приложение на омализумаб при деца – описание на 2 клинични случая

Публикувана на от admin

П.Костова, В.Папочиева, Г.Петрова

Клиника по педиатрия, УМБАЛ „Александровска“; Катедра по педиатрия, МУ-София

Резюме

IgE играе ключова роля предимно в алергичните заболявания. Все повече публикации насочват вниманието и на неговото участие при неалергични състояния, вкл. за успешно off-label приложение на анти-IgE перпарат (омализумаб) при заболявания като мастоцитоза, уртикария – васкулит, системен лупус еритематодес, булозни дерматози  и други.

Представяме нашия клиничен опит с off-label приложение на омализумаб при 2 деца: момче на 10 години с муковисцидоза и аспергилоза, и момиче на 9 години с нормокомплементарен уртикария-васкулит.

Ключови думи: Off-label, IgE, Омализумаб, алергични заболявания

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Библиография

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Адрес за кореспонденция:

Клиника по педиатрия, УМБАЛ “Александровска”, София  

Бул. “Г. Софийски”, 1  

1431, София

e-mail: poli.mu@gmail.com